Article
The association between cyclooxygenase-2 1195 G/A polymorphism and hepatocellular carcinoma: evidence from a meta-analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2013
Bu Xianmin, Zhao Chenghai
Abstract excerpt
Cyclooxygenase-2 (COX-2) is proven to influence the carcinogenesis through immune response suppression, apoptosis inhibition, angiogenesis regulation, and tumor cell invasion. Previous studies assessing the association between COX-2 1195 G/A polymorphism and susceptibility to hepatocellular carcinoma (HCC) reported conflicting results. The objective of the study was to investigate the association between COX-2...
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