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Article

COX-2 polymorphisms -765G→C and -1195A→G and hepatocellular carcinoma risk.

Gene - 15 Jun 2014

Gharib Aml F, Karam Rehab A, Abd El Rahman Tamer M, Elsawy Wael H

Abstract excerpt

Cyclooxygenase-2 (COX-2) is overexpressed in hepatocellular carcinoma (HCC) and considered to play a role in hepatic carcinogenesis. Our aim was to examine the associations between polymorphisms in COX-2 -765G→C and -1195A→G and risk of HCC. We conducted a case-control study including 120 patients with HCC and 130 age- and gender-matched controls. Genotypes of the COX-2 polymorphisms -765G→C and -1195A→G were...

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Identifiers

PMID: 24720952
DOI: 10.1016/j.gene.2014.04.014

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