Article
Dysregulation of Plasma miR-146a and miR-155 Expression Profile in Mycosis Fungoides Is Associated with rs2910164 and rs767649 Polymorphisms.
International journal of molecular sciences - 23 Dec 2022
Avgeros Chrysostomos, Patsatsi Aikaterini, Dimitriadis Dimitrios, Malousi Andigoni, Koletsa Triantafyllia, Papathemeli Despoina, Syrnioti Antonia, Avgerou Paraskevi, Lazaridou Elizabeth, Tzimagiorgis Georgios, Georgiou Elisavet
Abstract excerpt
Diagnosis of Mycosis Fungoides (MF) may be challenging, due to its polymorphic nature. The use of miRNAs as biomarkers to assist in diagnosis has been investigated, mainly in skin lesion biopsies. The purpose of this study is to evaluate the plasma levels of miR-146a and miR-155 in MF patients and to investigate their association with SNPs of their genes. Plasma miRNAs were quantified by RT-qPCR. Genomic DNA was...
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