Article
Potentially functional COX-2-1195G>A polymorphism increases the risk of digestive system cancers: a meta-analysis.
Journal of gastroenterology and hepatology - 1 Jun 2010
Dong Jing, Dai Juncheng, Zhang Mingfeng, Hu Zhibin, Shen Hongbing
Abstract excerpt
BACKGROUND AND AIM: Three potentially functional polymorphisms: -765G>C, -1195G>A, and 8473T>C in the cyclooxygenase-2 (COX-2) gene were identified and proposed to be associated with cancer susceptibility. The aim of this meta-analysis was to evaluate the association between these three polymorphisms and the risk of cancer in diverse populations. METHODS: All case-control studies published up to November 2009 on...
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