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Article

Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer.

Gastroenterology - 1 Aug 2005

Zhang Xuemei, Miao Xiaoping, Tan Wen, Ning Baitang, Liu Zhihua, Hong Yuan, Song Wenguang, Guo Yongli, Zhang Xinyu, Shen Yan, Qiang Boqin, Kadlubar Fred F, Lin Dongxin

Abstract excerpt

BACKGROUND & AIMS: Overexpression of cyclooxygenase-2 (COX-2) is implicated in many steps of cancer development. Single nucleotide polymorphisms (SNPs) in the COX-2 promoter might contribute to differential COX-2 expression and subsequent interindividual variability in susceptibility to cancer. This study sought to identify functional SNPs in the COX-2 promoter and evaluated their effects on the risk of...

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Source

Identifiers

PMID: 16083713
DOI: 10.1016/j.gastro.2005.05.003

Genes

MYB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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