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The Cox-2 -1195 G > A polymorphism and cancer risk: a meta-analysis of 25 case-control studies.

Mutagenesis - 1 Nov 2011

Tang Zhipeng, Nie Zhen-Lin, Pan Yuqin, Zhang Lirong, Gao Lei, Zhang Qian, Qu Lili, He Bangshun, Song Guoqi, Zhang Ying, Shukui Wang

Abstract excerpt

Cyclooxygenase 2 (Cox-2, a rate-limiting enzyme in the conversion of arachidonic acid to prostanoids) has been implicated in several physiological and pathological processes, and it has been reported that polymorphisms in the regulatory region of Cox-2 might influence its expression, contributing to the interindividual susceptibility to cancer. However, results from published studies on the association between...

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PMID: 21734230
DOI: 10.1093/mutage/ger040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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