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Article

A novel single nucleotide polymorphism of the cyclooxygenase-2 gene associated with breast cancer.

Clinical oncology (Royal College of Radiologists (Great Britain)) - 1 May 2009

Li F, Ren G S, Li H Y, Wang X Y, Chen L, Li J

Abstract excerpt

AIMS: Cyclooxygenase-2 (COX-2) is involved in carcinogenesis, immune response suppression, apoptosis inhibition, angiogenesis, and tumour cell invasion and metastasis. The gene for COX-2, designated as PTGS2, carries several polymorphisms, such as -765G >C, 1195G/A in the promoter region, and 8473T >C in the 3' UTR, which have been associated with susceptibility to malignant disease. The aim of this study was to...

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Source

Identifiers

PMID: 19138835
DOI: 10.1016/j.clon.2008.12.005

Genes

PTGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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