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Article

Nanopore Targeted Sequencing for Rapid Gene Mutations Detection in Acute Myeloid Leukemia.

Genes - 9 Dec 2019

Cumbo Cosimo, Minervini Crescenzio Francesco, Orsini Paola, Anelli Luisa, Zagaria Antonella, Minervini Angela, Coccaro Nicoletta, Impera Luciana, Tota Giuseppina, Parciante Elisa, Conserva Maria Rosa, Spinelli Orietta, Rambaldi Alessandro, Specchia Giorgina, Albano Francesco

Abstract excerpt

Acute myeloid leukemia (AML) clinical settings cannot do without molecular testing to confirm or rule out predictive biomarkers for prognostic stratification, in order to initiate or withhold targeted therapy. Next generation sequencing offers the advantage of the simultaneous investigation of numerous genes, but these methods remain expensive and time consuming. In this context, we present a nanopore-based assay...

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Identifiers

PMID: 31835432
DOI: 10.3390/genes10121026
PMCID: PMC6947272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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