Article

Ultrarapid Targeted Nanopore Sequencing for Fusion Detection of Leukemias

2022-06-23

Abstract excerpt

Acute leukemia (AL), a cancer of the blood, has continued high mortality rates despite a plethora of available treatments. Variable prognosis, treatment response and survival are largely based on distinct cytogenetic and molecular aberrations that characterize AL subtypes. Fast and cost-effective methods of detecting AL fusions and mutations are needed to improve clinical outcomes for patients. We report prelimina...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7708ce98-e611-5035-a443-acc8bc397daa
DOI: 10.1101/2022.06.20.22276664

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ultrarapid Targeted Nanopore Sequencing for Fusion Detection of LeukemiasDOI 10.1101/2022.06.20.22276664Read

Rapid detection of myeloid neoplasm fusions using Single Molecule Long-Read SequencingSemantic proximity Read

Nanopore Targeted Sequencing for Rapid Gene Mutations Detection in Acute Myeloid Leukemia.Semantic proximity Read

Nanopore sequencing of clonal IGH rearrangements in cell-free DNA as a biomarker for acute lymphoblastic leukemiaSemantic proximity Read

Partial Anchored Capture and Long-Read Sequencing (PACLseq) Enable a Stand-alone Diagnostic Method for Ph-like Acute Lymphoblastic LeukemiaSemantic proximity Read

Nanopore sequencing methods detect cell-free DNA associated with MRD and CNS infiltration in pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read

Advances in next-generation sequencing and emerging technologies for hematologic malignancies.Semantic proximity Read

Addressing the Global Diagnostics Gap for Childhood Leukemias: A Global, Multisite Type 2 Hybrid Validation Study of Nanopore-based Adaptive Sampling Whole Genome SequencingSemantic proximity Read

Targeted Next-Generation Sequencing of Acute Leukemia.Semantic proximity Read

Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing.Semantic proximity Read

Epigenomic diagnosis and prognosis of Acute Myeloid LeukemiaSemantic proximity Read

CRISPR-based rapid molecular diagnostic tests for fusion-driven leukemiasSemantic proximity Read

Oncogene Concatenated Enriched Amplicon Nanopore Sequencing for rapid, accurate, and affordable somatic mutation detection.Semantic proximity Read