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Article

Next-generation sequencing in the diagnosis and minimal residual disease assessment of acute myeloid leukemia

28 Mar 2019

Abstract excerpt

Risk-stratification of acute myeloid leukemia (AML) based on recurrent somatic abnormalities has evolved substantially in recent years, as illustrated by the current 2017 European LeukemiaNet (ELN) risk stratification.1 These 2017 ELN AML risk stratification recommendations are based on (cyto)genetic aberrations, including hotspot mutations such as those in NPM1, but also small insertions, deletions and point...

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PMID: 30923100
DOI: 10.3324/haematol.2018.205955

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