The utility of next-generation sequencing in diagnosis and monitoring of acute myeloid leukemia and myelodysplastic syndromes.

Abstract excerpt

Myeloid malignancies including acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) are a heterogeneous group of disorders that share a common biology and are a major source of morbidity and mortality. In the last several years, studies using next-generation sequencing (NGS) have identified a core set of recurrently mutated myeloid malignancy genes in the majority of patients with AML and MDS,...

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• Acute Disease
• High-Throughput Nucleotide Sequencing
• Leukemia, Myeloid
• Myelodysplastic Syndromes
• Nucleophosmin