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Article

Clinical Application of Next-Generation Sequencing-Based Panel to BRAF Wild-Type Advanced Melanoma Identifies Key Oncogenic Alterations and Therapeutic Strategies.

Molecular cancer therapeutics - 1 Mar 2020

Park Changhee, Kim Miso, Kim Min Jung, Kim Hyeongmin, Ock Chan-Young, Keam Bhumsuk, Kim Tae Min, Kim Dong-Wan, Kim Jong-Il, Heo Dae Seog

Abstract excerpt

Molecular profiling with next-generation sequencing (NGS) has been applied in multiple solid cancers to discover potential therapeutic targets. Here, we describe the results of a clinical NGS panel in patients with advanced melanoma. Thirty-six tumor tissues from patients with BRAF wild-type melanoma at Seoul National University Hospital (SNUH; Seoul, Republic of Korea) were collected and deep-sequenced using the...

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Share to Antineoplastic Agents, Immunological
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 31826932
DOI: 10.1158/1535-7163.MCT-19-0457

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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