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Exploring Molecular Genetic Alterations and RAF Fusions in Melanoma: A Belvarafenib Expanded Access Program in Patients with RAS/RAF-Mutant Melanoma.

The oncologist - 3 Jun 2024

Kim Kyoo Hyun, Cho Sungmin, Jeong Yeyeong, Baek Eun Sil, Lee Chung, Ryu Hyang-Joo, Noh Young Su, Hong Yoon-Hee, Chung Kee Yang, Roh Mi Ryung, Oh Byung Ho, Kim Chang Gon, Jung Minkyu, Shin Sang Joon

Abstract excerpt

BACKGROUND: Melanoma incidence is on the rise in East Asia, yet studies of the molecular landscape are lacking in this population. We examined patients with melanoma who underwent next-generation sequencing (NGS) at a single tertiary center in South Korea, focusing on patients harboring NRAS or RAF alterations who received belvarafenib, a pan-RAF dimer inhibitor, through the Expanded Access Program (EAP)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38470950
DOI: 10.1093/oncolo/oyae018
PMCID: PMC11144978

Genes

NRAS
BRAF
RAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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