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Article

Actionable Gene Alterations Identified in Patients With Malignant Melanoma by Targeted Sequencing in Japan.

JCO precision oncology - 1 Jan 2025

Noguchi Takuro, Ariga Shin, Moku Rika, Kikuchi Junko, Amano Toraji, Maeda Takuya, Ishikawa Kosuke, Maeda Taku, Shiiya Akihiko, Goda Tomohiro, Ohhara Yoshihito, Hagio Kanako, Saito Yusuke, Hatanaka Kanako C, Hatanaka Yutaka, Taguchi Jun, Takeuchi Satoshi, Shimizu Yasushi, Kinoshita Ichiro

Abstract excerpt

PURPOSE: Precision medicine plays an important role in the treatment of patients with advanced melanoma. Despite its high incidence in White patients, advanced melanoma is rare in Asian countries, hampering prospective clinical trials targeting the Asian population. This retrospective study aimed to elucidate the real-world molecular diagnoses and outcomes of Japanese patients with melanoma using comprehensive...

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Identifiers

PMID: 39823560
DOI: 10.1200/PO-24-00437
PMCID: PMC11753464

Genes

BRAF
KIT
NF1
NRAS

Variants

Provenance

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