Article
Towards Personalized Medicine in Melanoma: Implementation of a Clinical Next-Generation Sequencing Panel.
Scientific reports - 29 Mar 2017
de Unamuno Bustos Blanca, Murria Estal Rosa, Pérez Simó Gema, de Juan Jimenez Inmaculada, Escutia Muñoz Begoña, Rodríguez Serna Mercedes, Alegre de Miquel Victor, Llavador Ros Margarita, Ballester Sánchez Rosa, Nagore Enguídanos Eduardo, Palanca Suela Sarai, Botella Estrada Rafael
Abstract excerpt
Molecular diagnostics are increasingly performed routinely in the diagnosis and management of patients with melanoma due to the development of novel therapies that target specific genetic mutations. The development of next-generation sequencing (NGS) technologies has enabled to sequence multiple cancer-driving genes in a single assay, with improved sensitivity in mutation detection. The main objective of this...
Topics
- Aged
- Aged, 80 and over
- Biomarkers, Tumor
- Cell Line, Tumor
- Cost-Benefit Analysis
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genetic Testing