Article

Targeted DNA Sequencing of Cutaneous Melanoma Identifies Prognostic and Predictive Alterations

2024-01-22

Abstract excerpt

<h4>Importance</h4> Cutaneous melanoma (CM) can be molecularly classified into four groups: BRAF mutant, NRAS mutant, NF1 loss, and triple wild type (TWT) tumors lacking any of these three alterations. In the era of immune checkpoint inhibition (ICI) and targeted molecular therapy, the clinical significance of these groups remains unclear. Here, we integrate targeted DNA sequencing with comprehensive clinical...

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Literature Corpus work: c7d6d68a-c802-50c9-b601-a4d50fc3ae97
DOI: 10.1101/2024.01.18.576113

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