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Article

Genetic and epigenetic regulation of BHMT is associated with folate therapy efficacy in hyperhomocysteinaemia.

Asia Pacific journal of clinical nutrition - 1 Jan 2019

Li Dankang, Yang Jiao, Zhao Qinglin, Zhang Chengda, Ren Bingnan, Yue Limin, Du Binghui, Godfrey Opolot, Huang Xiaowen, Zhang Weidong

Abstract excerpt

BACKGROUND AND OBJECTIVES: Hyperhomocysteinaemia (HHcy) is an independent risk factors for several disorders, including cardiovascular disease. The understanding of the relationship among genetic, epigenetic and the efficacy of folate therapy for HHcy remain unclear. This study aim to investigate whether betaine-homocysteine methyltransferase (BHMT) single-nucleotide polymorphisms (SNPs) and DNA methylation are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 31826386
DOI: 10.6133/apjcn.201912_28(4).0025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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