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Article

A prospective cohort study of MTHFR C677T gene polymorphism and its influence on the therapeutic effect of homocysteine in stroke patients with hyperhomocysteinemia.

BMC neurology - 11 Apr 2020

Du Xiaoxia, Xiao Lin, Sun Rong, Li Kunpeng, Liang Lin, Song Luping, Liu Zhizhong

Abstract excerpt

BACKGROUND: Hyperhomocysteinemia (HHCY) is a risk factor for cardiovascular and cerebrovascular diseases. The C677T 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphism increases homocysteine (HCY) levels. This study analyzed the relationship between C677T MTHFR polymorphism and the therapeutic effect of lowering HCY in stroke patients with HHCY. METHODS: Baseline data were collected from stroke...

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Identifiers

PMID: 32278343
DOI: 10.1186/s12883-020-01701-8
PMCID: PMC7149884

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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