Article
Genetic polymorphisms of key enzymes in folate metabolism affect the efficacy of folate therapy in patients with hyperhomocysteinaemia.
The British journal of nutrition - 1 Apr 2018
Du Binghui, Tian Huizi, Tian Dandan, Zhang Chengda, Wang Wenhua, Wang Lianke, Ge Mengying, Hou Quanliang, Zhang Weidong
Abstract excerpt
The aim of this study is to analyse the efficacy rate of folate for the treatment of hyperhomocysteinaemia (HHcy) and to explore how folate metabolism-related gene polymorphisms change its efficacy. This study also explored the effects of gene-gene and gene-environment interactions on the efficacy of folate. A prospective cohort study enrolling HHcy patients was performed. The subjects were treated with oral...
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