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Article

Association of genetic and epigenetic variants in one-carbon metabolism gene with folate treatment response in hyperhomocysteinaemia.

European journal of clinical nutrition - 1 Jul 2020

Li Dankang, Zhao Qinglin, Huang Xiaowen, Zhang Chengda, Godfrey Opolot, Zhang Weidong

Abstract excerpt

BACKGROUND: Folate supplementation treatment is the first-line therapy in hyperhomocysteinaemia (HHcy). Up to 40% of HHcy patients do not benefit from folate therapy. Genetic and epigenetic factors of one-carbon metabolism (1-CM) might be identified as a predictor of folate supplementation treatment response. In the present study, we attempt to identify whether genetic and epigenetic factors might predict folate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Identifiers

PMID: 32203239
DOI: 10.1038/s41430-020-0611-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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