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Article

Integrating germline and somatic genetics to identify genes associated with lung cancer.

Genetic epidemiology - 1 Apr 2020

Pattee Jack, Zhan Xiaowei, Xiao Guanghua, Pan Wei

Abstract excerpt

Genome-wide association studies (GWAS) have successfully identified many genetic variants associated with complex traits. However, GWAS experience power issues, resulting in the failure to detect certain associated variants. Additionally, GWAS are often unable to parse the biological mechanisms of driving associations. An existing gene-based association test framework, Transcriptome-Wide Association Studies...

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Share to Gene Expression Regulation, Neoplastic
Share to Genes, Neoplasm
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31821614
DOI: 10.1002/gepi.22275
PMCID: PMC7064390

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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