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Article

Complement C5 Contributes to Brain Injury After Subarachnoid Hemorrhage.

Translational stroke research - 1 Aug 2020

van Dijk Bart J, Meijers Joost C M, Kloek Anne T, Knaup Veronique L, Rinkel Gabriel J E, Morgan B Paul, van der Kamp Marije J, Osuka Koji, Aronica Eleonora, Ruigrok Ynte M, van de Beek Diederik, Brouwer Matthijs, Pekna Marcela, Hol Elly M, Vergouwen Mervyn D I

Abstract excerpt

Previous studies showed that complement activation is associated with poor functional outcome after aneurysmal subarachnoid hemorrhage (SAH). We investigated whether complement activation is underlying brain injury after aneurysmal SAH (n = 7) and if it is an appropriate treatment target. We investigated complement expression in brain tissue of aneurysmal SAH patients (n = 930) and studied the role of common...

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Source

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Identifiers

PMID: 31811640
DOI: 10.1007/s12975-019-00757-0
PMCID: PMC7340633

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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