Article
Complement Factor H Y402H polymorphism is associated with an increased risk of mortality after intracerebral hemorrhage.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Nov 2011
Appelboom Geoffrey, Piazza Matthew, Hwang Brian Y, Bruce Samuel, Smith Steve, Bratt Alexander, Bagiella Emilia, Badjatia Neeraj, Mayer Stephan, Sander Connolly E
Abstract excerpt
Intracerebral hemorrhage (ICH) accounts for 10% to 15% of all strokes and is a major cause of morbidity and mortality. Despite advances in management, numerous clinical trials have failed to demonstrate significant benefit of medical and surgical interventions, underscoring the need for the identification of novel therapeutic targets based on improved understanding of ICH pathophysiology and optimal risk...
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