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Evolutionary History of the Toll-Like Receptor Gene Family across Vertebrates

2 Dec 2019

Abstract excerpt

Adaptation to a wide range of pathogenic environments is a major aspect of the ecological adaptations of vertebrates during evolution. Toll-like receptors (TLRs) are ancient membrane-bound sensors in animals and are best known for their roles in detecting and defense against invading pathogenic microorganisms. To understand the evolutionary history of the vertebrate TLR gene family, we first traced the origin of...

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PMID: 31800025
DOI: 10.1093/gbe/evz266

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