Article
Molecular evolution of the toll-like receptor multigene family in birds.
Molecular biology and evolution - 1 May 2011
Alcaide Miguel, Edwards Scott V
Abstract excerpt
Toll-like receptors (TLR) are membrane-bound sensors of the innate immune system that recognize invariant and distinctive molecular features of invading microbes and are also essential for initiating adaptive immunity in vertebrates. The genetic variation at TLR genes has been directly related to differential pathogen outcomes in humans and livestock. Nonetheless, new insights about the impact of TLRs...
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