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Article

Evolutionary divergence of TLR9 through ancestral sequence reconstruction.

Immunogenetics - 1 Jun 2024

Ghosh Manisha, Basak Surajit, Dutta Shanta

Abstract excerpt

The transmembrane pattern recognition receptor, Toll-like receptor (TLR), are best known for their roles in innate immunity via recognition of pathogen and initiation of signaling response. Mammalian TLRs recognize molecular patterns associated with pathogens and initiate innate immune response. We have studied the evolutionary diversity of mammalian TLR genes for differences in immunological response....

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PMID: 38441635
DOI: 10.1007/s00251-024-01338-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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