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Article

Significance of NOTCH1 mutations détections in T-acute lymphoblastic leukemia patients.

Cancer biomarkers : section A of Disease markers - 1 Jan 2020

Aref Salah, El Agdar Mohammed, Salama Osama, Zeid Tarek Abouzeid, Sabry Mohamed

Abstract excerpt

BACKGROUND: This study aimed to determine the prevalence and clinical impact of neurogenic locus notch homolog protein 1 (NOTCH1) mutations among patients with T cell acute lymphoblastic leukemia (T-ALL). PATIENT AND METHODS: A cohort of 60 T-ALL cases was included in this study. Sanger sequencing were done for NOTCH1 exon 26, 27, and distal part of exon 34 expanding the sequences encoding transcription...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 31796666
DOI: 10.3233/CBM-190967
PMCID: PMC12662283

Genes

NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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