Article
Clinical and biological relevance of genetic alterations in pediatric T‐cell acute lymphoblastic leukemia in Taiwan
2 Oct 2018
Abstract excerpt
BACKGROUND: The leukemogenesis of T-cell acute lymphoblastic leukemia (T-ALL) involves multistep processes of genetic alterations. We aimed to determine the genetic alterations including common fusion transcripts, overexpression of T-cell transcription factor oncogenes, and deletion or mutation of targeted genes in pediatric T-ALL in Taiwan as well as their impact on outcomes in those treated with the Taiwan...
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