Article
Mutation analysis in Korean patients with T-cell acute lymphoblastic leukemia.
Pediatric hematology and oncology - 1 Mar 2020
Park Kyoung-Jin, Kim In-Suk, Yang Eu Jeen, Lim Young Tak, Cho Su-Hee
Abstract excerpt
Genomic studies have illuminated the alterations in pathways underlying T-cell acute lymphoblastic leukemia (T-ALL) pathogenesis, but detailed mutation data by next-generation sequencing have not been reported in Korean patients. We aimed to investigate mutation frequency, spectrum, and pattern in the Korean patients with T-ALL. We designed a multigene panel targeting 101 genes and validated it using 10 reference...
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