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[Characteristics of NOTCH1 mutation in adult T-cell acute lymphoblastic leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Dec 2013

Lin Zhong-Kun, Zhang Run, Ge Zheng, Liu Juan, Guo Xing, Qiao Chun, Wu Yu-Jie, Qiu Hai-Rong, Zhang Jian-Fu, Li Jian-Yong

Abstract excerpt

This study was aimed to investigate the characteristics and clinical significance of NOTCH1 mutation in adult T-cell acute lymphoblastic leukemia (T-ALL). Exon 26/N-terminal region of the heterodimerization domain (HD-N) , exon 27/ C-terminal region of the heterodimerization domain (HD-C) , exon 28 and exon 34/ proline-glutamic acid-serine-threonine (PEST) domain of the NOTCH1 gene were amplified, cloned and...

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Adolescent
Base Sequence
NOTCH1 gene
Genotype
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Receptor, Notch1

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Identifiers

PMID: 24370020
DOI: 10.7534/j.issn.1009-2137.2013.06.008

Genes

NOTCH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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