Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical Value of NOTCH1 Mutations Detection among Chronic Lymphocytic Leukemia Patients.

Asian Pacific journal of cancer prevention : APJCP - 1 May 2020

Aref Salah, El-Agder Mohamed, Salama Osama, Abouzeid Tarek, Sabry Mohamed

Abstract excerpt

BACKGROUND: The data about the clinical impact of NOTCH1 mutations among Egyptians B - cell chronic lymphocytic patients is not previously identified. We herein, evaluate the prevalence and the prognostic significance of neurogenic locus notch homolog protein-1 (NOTCH1) mutations in B- cell lymphocytic leukemia (B-CLL). METHODS: A cohort of 105 Egyptian B-CLL patients aging from 43 to 86 years. PCR products...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Combined Chemotherapy Protocols
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Follow-Up Studies

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Receptor, Notch1

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 32458636
DOI: 10.31557/APJCP.2020.21.5.1295
PMCID: PMC7541881

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical Value of NOTCH1 Mutations Detection among Chronic Lymphocytic Leukemia Patients.PMID 32458636Read ↗

NOTCH1 mutation and its prognostic significance in Chinese chronic lymphocytic leukemia: a retrospective study of 317 cases.Semantic proximity Read ↗

Significance of NOTCH1 mutations détections in T-acute lymphoblastic leukemia patients.Semantic proximity Read ↗

Multiple Mechanisms of NOTCH1 Activation in Chronic Lymphocytic Leukemia: NOTCH1 Mutations and BeyondSemantic proximity Read ↗

Prognostic impact and landscape of NOTCH1 mutations in chronic lymphocytic leukemia (CLL): a study on 852 patientsSemantic proximity Read ↗

Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia.Semantic proximity Read ↗

NOTCH1 PEST domain mutation is an adverse prognostic factor in B‐CLLSemantic proximity Read ↗

NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome.Semantic proximity Read ↗

NOTCH1 mutations are associated with favourable long-term prognosis in paediatric T-cell acute lymphoblastic leukaemia: a retrospective study of patients treated on BCH-2003 and CCLG-2008 protocol in China.Semantic proximity Read ↗

Landscape of NOTCH1 mutations and co-occurring biomarker alterations in chronic lymphocytic leukemia.Semantic proximity Read ↗

Characteristics of chronic lymphocytic leukemia with somatically acquired mutations in NOTCH1 exon 34Semantic proximity Read ↗

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.Semantic proximity Read ↗

NOTCH-1 Gene Mutations Influence Survival in Acute Myeloid Leukemia Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.