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Genetic predisposition to central nervous system tumors in children - what the neurosurgeon should know.

Acta neurochirurgica - 1 Nov 2022

Foss-Skiftesvik Jon, Stoltze Ulrik Kristoffer

Abstract excerpt

BACKGROUND: Historically, few pediatric central nervous system (CNS) tumors were thought to result from genetic predisposition. However, within the last decade, new DNA sequencing methods have led to an increased recognition of high-risk cancer predisposition syndromes in children with CNS tumors. Thus, genetic predisposition is increasingly impacting clinical pediatric neuro-oncology. METHODS: In this narrative...

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PMID: 35660974
DOI: 10.1007/s00701-022-05258-y

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