Article
Brain tumor susceptibility: From genetic predisposition syndromes to extended characterization of genomic determinants.
Critical reviews in oncology/hematology - 1 Sept 2026
Aprile Marta, Callegari Vanessa, Cipri Selene, Di Nunno Vincenzo, Gatto Lidia, Tosoni Alicia, Dima Giovanni, Argento Chiara Maria, Bartolini Stefania, Margotti Marzia, Baldo Giada Del, Cacchione Antonella, Chiavelli Chiara, Roncucci Luca, Toss Angela, Depenni Roberta, Ratti Stefano, Dominici Massimo, Mastronuzzi Angela, Franceschi Enrico
Abstract excerpt
There is still a lack of knowledge regarding the aetiology of central nervous system (CNS) tumors and the risk factors that predispose to their development. Some mutated genes are well known to be causative agents for tumorigenesis. In the most recent classification of CNS tumors, 19 genetic syndromes were correlated with brain neoplasms. Genetic predisposition has also been suspected outside hereditary...
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