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Article

PRMT1 suppresses ATF4-mediated endoplasmic reticulum response in cardiomyocytes.

Cell death & disease - 2 Dec 2019

Jeong Myong-Ho, Jeong Hyeon-Ju, Ahn Byeong-Yun, Pyun Jung-Hoon, Kwon Ilmin, Cho Hana, Kang Jong-Sun

Abstract excerpt

Endoplasmic reticulum (ER) stress signaling plays a critical role in the control of cell survival or death. Persistent ER stress activates proapoptotic pathway involving the ATF4/CHOP axis. Although accumulating evidences support its important contribution to cardiovascular diseases, but its mechanism is not well characterized. Here, we demonstrate a critical role for PRMT1 in the control of ER stress in...

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Source

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Identifiers

PMID: 31787756
DOI: 10.1038/s41419-019-2147-3
PMCID: PMC6885520

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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