Article

ATF3 is required for the prevention of cardiomyopathy via the regulation of mitochondrial oxidative stress

2024-07-15

Abstract excerpt

<title>Abstract</title> <p>Activating transcription factor 3 (ATF3) is a critical regulator for cellular stress responses and is implicated in stress-induced cardiac hypertrophy and fibrosis. However, the role of ATF3 in cardiomyopathy remains controversial. Here, we demonstrate that ATF3 plays a cardioprotective role by controlling mitochondrial oxidative stress in angiotensin II (Ang II)-triggered cardiomyopath...

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Literature Corpus work: acf0e5fa-33f9-5489-81f0-d4483bd3b91b
DOI: 10.21203/rs.3.rs-4485671/v1

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