Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ATF6 Is a Transcription Factor Specializing in the Regulation of Quality Control Proteins in the Endoplasmic Reticulum

1 Jan 2008

Abstract excerpt

Eukaryotic cells cope with endoplasmic reticulum (ER) stress by activating the unfolded protein response (UPR), a coordinated system of transcriptional and translational controls, which ensures the integrity of synthesized proteins. Mammalian cells express three UPR transducers in the ER, namely IRE1, PERK and ATF6. The IRE1 pathway, which is conserved from yeast to humans, mediates transcriptional induction of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Endoplasmic Reticulum Stress and Disease
Share to Fungal and yeast genetics research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18360008
DOI: 10.1247/csf.07044

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ATF6 Is a Transcription Factor Specializing in the Regulation of Quality Control Proteins in the Endoplasmic ReticulumPMID 18360008Read ↗

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress.Semantic proximity Read ↗

Molecular mechanism of ATF6 in unfolded protein response and its role in diseaseSemantic proximity Read ↗

Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum.Semantic proximity Read ↗

The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiologySemantic proximity Read ↗

Physiological unfolded protein response regulated by OASIS family members, transmembrane bZIP transcription factorsSemantic proximity Read ↗

Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulumSemantic proximity Read ↗

The UPRosome – decoding novel biological outputs of IRE1α functionSemantic proximity Read ↗

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein ResponseSemantic proximity Read ↗

Roles of XBP1s in Transcriptional Regulation of Target GenesSemantic proximity Read ↗

Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and DiseaseSemantic proximity Read ↗

Signaling Pathways from the Endoplasmic Reticulum and Their Roles in DiseaseSemantic proximity Read ↗

Master Regulator Activating Transcription Factor 3 (ATF3) in Metabolic Homeostasis and CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.