Article
Quantitative Trait Module-Based Genetic Analysis of Alzheimer's Disease.
International journal of molecular sciences - 25 Nov 2019
Yuan Shaoxun, Li Haitao, Xie Jianming, Sun Xiao
Abstract excerpt
The pathological features of Alzheimer's Disease (AD) first appear in the medial temporal lobe and then in other brain structures with the development of the disease. In this work, we investigated the association between genetic loci and subcortical structure volumes of AD on 393 samples in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort. Brain subcortical structures were clustered into modules...
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