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Article

Network-based analysis of genetic variants associated with hippocampal volume in Alzheimer’s disease: a study of ADNI cohorts

19 Jan 2016

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disease that causes dementia. While molecular basis of AD is not fully understood, genetic factors are expected to participate in the development and progression of the disease. Our goal was to uncover novel genetic underpinnings of Alzheimer's disease with a bioinformatics approach that accounts for tissue specificity. FINDINGS: We performed genome-wide...

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PMID: 26788126
DOI: 10.1186/s13040-016-0082-8

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