Article
Genome-wide Network-assisted Association and Enrichment Study of Amyloid Imaging Phenotype in Alzheimer's Disease.
Current Alzheimer research - 1 Jan 2019
Li Jin, Chen Feng, Zhang Qiushi, Meng Xianglian, Yao Xiaohui, Risacher Shannon L, Yan Jingwen, Saykin Andrew J, Liang Hong, Shen Li
Abstract excerpt
BACKGROUND: The etiology of Alzheimer's disease remains poorly understood at the mechanistic level, and genome-wide network-based genetics have the potential to provide new insights into the disease mechanisms. OBJECTIVE: The study aimed to explore the collective effects of multiple genetic association signals on an AV-45 PET measure, which is a well-known Alzheimer's disease biomarker, by employing a network...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.