Article
Integrative analyses of neuroimaging, clinical, and multi-omics data identified meaningful Alzheimer’s disease progression subtypes
2022-11-02
Abstract excerpt
Alzheimer’s Disease (AD) is a common neurodegenerative disorder with diverse clinical manifestations. To better understand differences between diverse manifestations, we investigate from the difference in MRI ROI volumes among subtypes to their related different gene pathways. In this study, we identify three subtypes of AD development with fast, moderate, and slow progression rates from the MRI ROI volume biomark...
Topics
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- Alzheimer's disease research and treatments
- Bioinformatics and Genomic Networks
- Dementia and Cognitive Impairment Research
- Epigenetics and DNA Methylation
- Immune cells in cancer
- Metabolomics and Mass Spectrometry Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
Identifiers and source
- Literature Corpus work
- a46c36cf-84d2-50ef-8f2b-b1b064c94900
- DOI
- 10.1101/2022.11.01.22281820
