Article
Identification and functional validation of genetic variants in potential miRNA target sites of established BMI genes.
International journal of obesity (2005) - 1 May 2020
Kumar Pankaj, Traurig Michael, Baier Leslie J
Abstract excerpt
OBJECTIVE: MicroRNAs (miRNAs) play an important role in posttranscriptional regulation by binding to target sites in the 3'UTR of protein-coding genes. Genetic variation within target sites may potentially disrupt the binding activity of miRNAs, thereby impacting this regulation. In the current study, we investigated whether any established BMI-associated genetic variants potentially function by altering a miRNA...
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