miRdSNP: a database of disease-associated SNPs and microRNA target sites on 3'UTRs of human genes.

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) can lead to the susceptibility and onset of diseases through their effects on gene expression at the posttranscriptional level. Recent findings indicate that SNPs could create, destroy, or modify the efficiency of miRNA binding to the 3'UTR of a gene, resulting in gene dysregulation. With the rapidly growing number of published disease-associated SNPs (dSNPs),...

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• 3' Untranslated Regions
• Algorithms
• Databases, Genetic
• Disease
• Internet