Article
Identification and characterization of the long non-coding RNA NFIA-AS2 as a novel locus for body mass index in American Indians.
International journal of obesity (2005) - 1 Jun 2023
Bandesh Khushdeep, Traurig Michael, Chen Peng, Hsueh Wen-Chi, Hanson Robert L, Piaggi Paolo, Baier Leslie J
Abstract excerpt
BACKGROUND: Genome-wide association studies have shown that body mass index (BMI), an estimate of obesity, is highly polygenic. Individual variants typically have small effect sizes, making it challenging to identify unique loci in under-represented ethnic groups which lack statistical power due to their small sample size. Yet obesity is a major health disparity and is particularly prevalent in southwestern...
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