Article
Association of miRNA targetome variants in LAMC1 and GNB3 genes with colorectal cancer and obesity.
Cancer medicine - 1 Nov 2022
Gholami Morteza, Zoughi Marziyeh, Behboo Roobic, Taslimi Reza, Kazemeini Alireza, Bastami Milad, Hasani-Ranjbar Shirin, Larijani Bagher, Amoli Mahsa M
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) is one of the most common obesity-associated cancers. Inflammation is also considered the most important factor between obesity and CRC. This study aimed to examine miRNAs binding sites variants on inflammatory genes identified using bioinformatics and systematic approach on clinical samples that were collected from CRC patients and controls. METHODS: The candidate variants...
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