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Article

Lack of NPY in neurotensin neurons leads to a lean phenotype.

Neuropeptides - 1 Apr 2020

Lee Nicola J, Qi Yue, Enriquez Ronaldo F, Ip Chi Kin, Herzog Herbert

Abstract excerpt

Neuropeptide Y (NPY) producing neurons in the arcuate nucleus (Arc) of the hypothalamus are essential to the regulation of food intake and energy homeostasis. Whilst they have classically been thought to co-express agouti-related peptide (AgRP), it is now clear that there is a sub-population of NPY neurons in the Arc that do not. Here, we show that a subset of AgRP-negative, NPY-positive neurons in the Arc also...

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Source

Identifiers

PMID: 31740068
DOI: 10.1016/j.npep.2019.101994

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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