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Article

Activation of Stat3 signaling in AgRP neurons promotes locomotor activity.

Cell metabolism - 1 Mar 2008

Mesaros Andrea, Koralov Sergei B, Rother Eva, Wunderlich F Thomas, Ernst Marianne B, Barsh Gregory S, Rajewsky Klaus, Brüning Jens C

Abstract excerpt

Leptin, an adipocyte-derived hormone, acts on hypothalamic neurons located in the arcuate nucleus (ARC) of the hypothalamus to regulate energy homeostasis. One of the leptin-regulated neuronal subtypes in the ARC are agouti-related peptide (AgRP)-expressing neurons, which are involved in the regu...

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Identifiers

PMID: 18316029
DOI: 10.1016/j.cmet.2008.01.007

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ARC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18316029-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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