Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An inhibitor of potentially lethal damage (PLD) repair reduces the frequency of gamma-ray-induced mutations in cultured Chinese hamster V79 cells.

Mutation research - 1 Aug 1992

Yokoiyama A, Kada T, Kuroda Y

Abstract excerpt

Cordycepin (3'-deoxyadenosine, 3'-dA) is an RNA antimetabolite and a radiosensitizer in cultured mammalian cells. In the present paper, the effects of 3'-dA on gamma-ray-induced lethality and 6-thioguanine (6TG)-resistant mutations in cultured Chinese hamster V79 cells were examined. 3'-dA had the effect of sensitizing the lethality induced by gamma-rays. The potentially lethal damage (PLD) repair produced by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Cell Survival
Share to Cricetinae

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cricetulus

Share to DNA Repair

Share to Gamma Rays

Share to Mutation

Source

Identifiers

PMID: 1379331
DOI: 10.1016/0027-5107(92)90231-p

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An inhibitor of potentially lethal damage (PLD) repair reduces the frequency of gamma-ray-induced mutations in cultured Chinese hamster V79 cells.PMID 1379331Read ↗

Bystander effects may modulate ultraviolet A and B radiation-induced delayed mutagenesis.Semantic proximity Read ↗

Mutagenicity of oxidative DNA damage in Chinese hamster V79 cells.Semantic proximity Read ↗

The biological effects of N3-methyladenine.Semantic proximity Read ↗

Contribution of O6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: new insights gained from studies of genetically engineered mammalian cell lines.Semantic proximity Read ↗

Nucleoside and nucleobase analog mutagens.Semantic proximity Read ↗

Delayed appearance of lethal and specific gene mutations in irradiated mammalian cells.Semantic proximity Read ↗

Sapacitabine, the prodrug of CNDAC, is a nucleoside analog with a unique action mechanism of inducing DNA strand breaksSemantic proximity Read ↗

Antimutagenic activity of vitamins in cultured mammalian cells.Semantic proximity Read ↗

X-ray-induced bystander responses reduce spontaneous mutations in V79 cells.Semantic proximity Read ↗

Isolation and partial characterisation of a mammalian cell mutant hypersensitive to topoisomerase II inhibitors and X-rays.Semantic proximity Read ↗

Strand- and sequence-specific attenuation of N-methyl-N'-nitro-N-nitrosoguanidine-induced G.C to A.T transitions by expression of human 6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells.Semantic proximity Read ↗

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.