Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tracking the Stepwise Movement of a Membrane-inserting Protein In Vivo.

Journal of molecular biology - 17 Jan 2020

He Haoze, Kuhn Andreas, Dalbey Ross E

Abstract excerpt

Proper membrane insertion is crucial for the structure and function of membrane proteins in all cells. The YidC insertase plays an essential role in this process, but the molecular mechanism of YidC-mediated insertion remains unknown. Here we track the stepwise movement of Pf3 coat through YidC by obtaining a series of translational arrested intermediates, and investigate them by thiol cross-linking. We show that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Membrane
Share to Escherichia coli Proteins
Share to Hydrophobic and Hydrophilic Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Transport Proteins

Share to Periplasm

Share to Protein Biosynthesis

Share to Protein Transport

Share to Substrate Specificity

Source

Identifiers

PMID: 31669168
DOI: 10.1016/j.jmb.2019.10.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tracking the Stepwise Movement of a Membrane-inserting Protein In Vivo.PMID 31669168Read ↗

The Pf3 coat protein contacts TM1 and TM3 of YidC during membrane biogenesis.Semantic proximity Read ↗

Dynamic disulfide scanning of the membrane-inserting Pf3 coat protein reveals multiple YidC substrate contacts.Semantic proximity Read ↗

Monitoring the binding and insertion of a single transmembrane protein by an insertase.Semantic proximity Read ↗

Real time observation of single membrane protein insertion events by the Escherichia coli insertase YidC.Semantic proximity Read ↗

Membrane protein sequence features direct post-translational insertionSemantic proximity Read ↗

Substrate-dependent conformational dynamics of the Escherichia coli membrane insertase YidC.Semantic proximity Read ↗

Features of membrane protein sequence direct post-translational insertion.Semantic proximity Read ↗

Insertion and glycosylation of Pf3-derived membrane proteins in microsomes.Semantic proximity Read ↗

The conserved third transmembrane segment of YidC contacts nascent Escherichia coli inner membrane proteins.Semantic proximity Read ↗

Structure of a bacterial type III secretion system in contact with a host membrane in situSemantic proximity Read ↗

The architecture of EMC reveals a path for membrane protein insertionSemantic proximity Read ↗

Conserved Salt Bridges Facilitate Assembly of the Helical Core Export Apparatus of a Salmonella enterica Type III Secretion System.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.