Article
Insertion and glycosylation of Pf3-derived membrane proteins in microsomes.
FEBS letters - 13 Feb 2002
Ridder Anja, Thissen Laura, Killian Antoinette, de Kruijff Ben
Abstract excerpt
To get insight into the insertion mechanism of small newly synthesized single-spanning membrane proteins, Pf3 coat protein mutants were constructed with potential glycosylation sites in the N-terminus. Some of these proteins, when synthesized in vitro in the presence of microsomes, became efficiently glycosylated, proving that they insert into the membrane and translocate their N-terminus to the lumenal side....
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