Article
Direct sequencing of RNA with MinION Nanopore: detecting mutations based on associations.
Nucleic acids research - 16 Dec 2019
Harel Noam, Meir Moran, Gophna Uri, Stern Adi
Abstract excerpt
One of the key challenges in the field of genetics is the inference of haplotypes from next generation sequencing data. The MinION Oxford Nanopore sequencer allows sequencing long reads, with the potential of sequencing complete genes, and even complete genomes of viruses, in individual reads. However, MinION suffers from high error rates, rendering the detection of true variants difficult. Here, we propose a new...
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